Gastrointestinal lymphoma in cats

An actual mass can potentially cause obstruction in the intestine and lead to a crisis that must be promptly resolved with surgery. It is unknown whether these cats would do better with a higher-grade protocol. Progressive lack of appetite, lethargy and weight loss are among the most common. Otherwise, despite rigorous data analysis in multiple studies, there is no consistent association with any patient or tumour characteristic that is predictive of outcome including gastrointestinal lymphoma in cats, immunophenotype, clinical stage, age and bodyweight. The histologic classification of cases of feline lymphoproliferative disease using the National Cancer Institute working formulation. Older studies suggested that the gastrointestinal location was gastrointestinal lymphoma in cats common than other anatomical locations, however more recent studies suggest that a gastrointestinal location is the most common site.
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Sixty-nine percent of cats in this study achieved complete remission with a median disease-free interval of In all three cats, this apparent chlorambucil-induced neurotoxicity was self-limiting after the drug was discontinued. Chlorambucil in indolent chronic lymphocytic leukemia.

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Treatment of Feline Gastrointestinal Small-Cell Lymphoma With Chlorambucil and Glucocorticoids

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The response to doxorubicin alone is generally poorer than that to other protocols; thus this drug should not be used as a sole chemotherapy agent for GI lymphoma. Cyclophosphamide can also cause sterile hemorrhagic cystitis; however, this problem is rare in cats.

Treatment of Feline Gastrointestinal Small-Cell Lymphoma With Chlorambucil and Glucocorticoids

For example, some schemes describing feline gastrointestinal lymphoma (GI LSA ) include hepatic or splenic involvement, whereas others include this pattern as. Gastrointestinal (GI) lymphoma is the most frequently diagnosed form of lymphoma in the cat and is categorized into two distinct forms based on the size of. However, cats more commonly develop gastrointestinal (GI) lymphoma, typically without generalized lymphadenopathy. Clinical signs of.
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A CBC and serum chemistry profile should be conducted before treatment, then weekly for the first month of treatment and every 3 months thereafter. There are no right or wrong answers, and each situation is different. It is rare to cure lymphoma.

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Cyclophosphamide can also cause sterile hemorrhagic cystitis; however, this problem is rare in cats. Cats that achieved complete remission generally had longer survival times than did cats failing to achieve remission. Cats with lymphoma who are not treated with chemotherapy have an average survival time of 4 weeks once the diagnosis has been made. Details of the remaining five ultrasounds either gave no description of intestinal thickness or were unavailable for review. The purpose of this study is to describe the treatment of feline GI small-cell lymphoma with chlorambucil and glucocorticoids within a well-defined case population. Since other studies did not compare low-grade and high-grade lymphoma, this finding has not been described by others.
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Clinical signs of lymphoma in cats also tend to be nonspecific, mimicking those of a range of other conditions such as pancreatitis and renal failure.
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Gastrointestinal (GI) (or alimentary) lymphoma is the most common form of lymphoma in cats. Feline GI lymphoma is histologically classified as. Therefore, clinical signs of lymphoma are often similar to other intestinal diseases . Lymphoma cannot be prevented, but the likelihood of a cat developing. Diagnosis of lymphoma in cats is based on a series of observations and tests. A physical exam may reveal swellings in the lymph nodes or the gastrointestinal.
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